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Cyclin E1 Expression and Palbociclib Efficacy in Previously Treated Hormone Receptor–Positive Metastatic Breast Cancer

PURPOSE: A large-panel gene expression analysis was conducted to identify biomarkers associated with the effectiveness of adding palbociclib to fulvestrant. METHODS: The PALOMA-3 (ClinicalTrials.gov identifier: NCT01942135) trial randomly assigned 521 endocrine-pretreated patients with metastatic br...

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Detalles Bibliográficos
Autores principales: Turner, Nicholas C., Liu, Yuan, Zhu, Zhou, Loi, Sherene, Colleoni, Marco, Loibl, Sibylle, DeMichele, Angela, Harbeck, Nadia, André, Fabrice, Bayar, Mohamed Amine, Michiels, Stefan, Zhang, Zhe, Giorgetti, Carla, Arnedos, Monica, Huang Bartlett, Cynthia, Cristofanilli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506420/
https://www.ncbi.nlm.nih.gov/pubmed/30807234
http://dx.doi.org/10.1200/JCO.18.00925