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Comparative mode of action of the antimicrobial peptide melimine and its derivative Mel4 against Pseudomonas aeruginosa

Melimine and Mel4 are chimeric cationic peptides with broad-spectrum antimicrobial activity. They have been shown to be highly biocompatible in animal models and human clinical trials. The current study examined the mechanism of action of these two antimicrobial peptides against P. aeruginosa. The e...

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Detalles Bibliográficos
Autores principales: Yasir, Muhammad, Dutta, Debarun, Willcox, Mark D. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506473/
https://www.ncbi.nlm.nih.gov/pubmed/31068610
http://dx.doi.org/10.1038/s41598-019-42440-2