Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease

Ribosome biogenesis is a canonical hallmark of cell growth and proliferation. Here we show that execution of Epithelial-to-Mesenchymal Transition (EMT), a migratory cellular program associated with development and tumor metastasis, is fueled by upregulation of ribosome biogenesis during G1/S arrest....

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Detalles Bibliográficos
Autores principales: Prakash, Varsha, Carson, Brittany B., Feenstra, Jennifer M., Dass, Randall A., Sekyrova, Petra, Hoshino, Ayuko, Petersen, Julian, Guo, Yuan, Parks, Matthew M., Kurylo, Chad M., Batchelder, Jake E., Haller, Kristian, Hashimoto, Ayako, Rundqivst, Helene, Condeelis, John S., Allis, C. David, Drygin, Denis, Nieto, M. Angela, Andäng, Michael, Percipalle, Piergiorgio, Bergh, Jonas, Adameyko, Igor, Farrants, Ann-Kristin Östlund, Hartman, Johan, Lyden, David, Pietras, Kristian, Blanchard, Scott C., Vincent, C. Theresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506521/
https://www.ncbi.nlm.nih.gov/pubmed/31068593
http://dx.doi.org/10.1038/s41467-019-10100-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506521/
https://www.ncbi.nlm.nih.gov/pubmed/31068593
http://dx.doi.org/10.1038/s41467-019-10100-8

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