Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2

Dna2 is an essential nuclease-helicase that acts in several distinct DNA metabolic pathways including DNA replication and recombination. To balance these functions and prevent unscheduled DNA degradation, Dna2 activities must be regulated. Here we show that Saccharomyces cerevisiae Dna2 function is...

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Detalles Bibliográficos
Autores principales: Ranjha, Lepakshi, Levikova, Maryna, Altmannova, Veronika, Krejci, Lumir, Cejka, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506525/
https://www.ncbi.nlm.nih.gov/pubmed/31098407
http://dx.doi.org/10.1038/s42003-019-0428-0