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Initial state of DNA-Dye complex sets the stage for protein induced fluorescence modulation

Protein-induced fluorescence enhancement (PIFE) is a popular tool for characterizing protein-DNA interactions. PIFE has been explained by an increase in local viscosity due to the presence of the protein residues. This explanation, however, denies the opposite effect of fluorescence quenching. This...

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Detalles Bibliográficos
Autores principales: Rashid, Fahad, Raducanu, Vlad-Stefan, Zaher, Manal S., Tehseen, Muhammad, Habuchi, Satoshi, Hamdan, Samir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506533/
https://www.ncbi.nlm.nih.gov/pubmed/31068591
http://dx.doi.org/10.1038/s41467-019-10137-9