Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Gene editing by CRISPR/Cas9 is commonly used to generate germline mutations or perform in vitro screens, but applicability for in vivo screening has so far been limited. Recently, it was shown that in Drosophila, Cas9 expression could be limited to a desired group of cells, allowing tissue-specific...

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Detalles Bibliográficos
Autores principales: Meltzer, Hagar, Marom, Efrat, Alyagor, Idan, Mayseless, Oded, Berkun, Victoria, Segal-Gilboa, Netta, Unger, Tamar, Luginbuhl, David, Schuldiner, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506539/
https://www.ncbi.nlm.nih.gov/pubmed/31068592
http://dx.doi.org/10.1038/s41467-019-10140-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506539/
https://www.ncbi.nlm.nih.gov/pubmed/31068592
http://dx.doi.org/10.1038/s41467-019-10140-0

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