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Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila
Gene editing by CRISPR/Cas9 is commonly used to generate germline mutations or perform in vitro screens, but applicability for in vivo screening has so far been limited. Recently, it was shown that in Drosophila, Cas9 expression could be limited to a desired group of cells, allowing tissue-specific...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506539/ https://www.ncbi.nlm.nih.gov/pubmed/31068592 http://dx.doi.org/10.1038/s41467-019-10140-0 |