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Transient opening of trimeric prefusion RSV F proteins

The respiratory syncytial virus (RSV) F glycoprotein is a class I fusion protein that mediates viral entry and is a major target of neutralizing antibodies. Structures of prefusion forms of RSV F, as well as other class I fusion proteins, have revealed compact trimeric arrangements, yet whether thes...

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Detalles Bibliográficos
Autores principales: Gilman, Morgan S. A., Furmanova-Hollenstein, Polina, Pascual, Gabriel, B. van ‘t Wout, Angélique, Langedijk, Johannes P. M., McLellan, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506550/
https://www.ncbi.nlm.nih.gov/pubmed/31068578
http://dx.doi.org/10.1038/s41467-019-09807-5