Enhancing MicroRNA Activity through Increased Endosomal Release Mediated by Nigericin

The therapeutic promise of small-RNA therapeutics is limited, not only by the lack of delivery vehicles, but also by the inability of the small RNAs to reach intracellular compartments where they can be biologically active. We previously reported successful delivery of functionally active miRNAs via...

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Detalles Bibliográficos
Autores principales: Orellana, Esteban A., Abdelaal, Ahmed M., Rangasamy, Loganathan, Tenneti, Srinivasarao, Myoung, Sunghyun, Low, Philip S., Kasinski, Andrea L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506612/
https://www.ncbi.nlm.nih.gov/pubmed/31071527
http://dx.doi.org/10.1016/j.omtn.2019.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506612/
https://www.ncbi.nlm.nih.gov/pubmed/31071527
http://dx.doi.org/10.1016/j.omtn.2019.04.003

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