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Enhancing MicroRNA Activity through Increased Endosomal Release Mediated by Nigericin
The therapeutic promise of small-RNA therapeutics is limited, not only by the lack of delivery vehicles, but also by the inability of the small RNAs to reach intracellular compartments where they can be biologically active. We previously reported successful delivery of functionally active miRNAs via...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506612/ https://www.ncbi.nlm.nih.gov/pubmed/31071527 http://dx.doi.org/10.1016/j.omtn.2019.04.003 |