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Genomewide Profiling of the Enterococcus faecalis Transcriptional Response to Teixobactin Reveals CroRS as an Essential Regulator of Antimicrobial Tolerance

Teixobactin is a new antimicrobial of significant interest. It is active against a number of multidrug-resistant pathogens, including Staphylococcus aureus and Enterococcus faecalis, with no reported mechanisms of teixobactin resistance. However, historically, mechanisms of resistance always exist a...

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Detalles Bibliográficos
Autores principales: Darnell, Rachel L., Knottenbelt, Melanie K., Todd Rose, Francesca O., Monk, Ian R., Stinear, Timothy P., Cook, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506618/
https://www.ncbi.nlm.nih.gov/pubmed/31068434
http://dx.doi.org/10.1128/mSphere.00228-19