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Comprehensive Genetic Characterization of Mitochondrial Ca(2+) Uniporter Components Reveals Their Different Physiological Requirements In Vivo

Mitochondrial Ca(2+) uptake is an important mediator of metabolism and cell death. Identification of components of the highly conserved mitochondrial Ca(2+) uniporter has opened it up to genetic analysis in model organisms. Here, we report a comprehensive genetic characterization of all known unipor...

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Detalles Bibliográficos
Autores principales: Tufi, Roberta, Gleeson, Thomas P., von Stockum, Sophia, Hewitt, Victoria L., Lee, Juliette J., Terriente-Felix, Ana, Sanchez-Martinez, Alvaro, Ziviani, Elena, Whitworth, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506686/
https://www.ncbi.nlm.nih.gov/pubmed/31042479
http://dx.doi.org/10.1016/j.celrep.2019.04.033