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Comprehensive Genetic Characterization of Mitochondrial Ca(2+) Uniporter Components Reveals Their Different Physiological Requirements In Vivo
Mitochondrial Ca(2+) uptake is an important mediator of metabolism and cell death. Identification of components of the highly conserved mitochondrial Ca(2+) uniporter has opened it up to genetic analysis in model organisms. Here, we report a comprehensive genetic characterization of all known unipor...
Autores principales: | Tufi, Roberta, Gleeson, Thomas P., von Stockum, Sophia, Hewitt, Victoria L., Lee, Juliette J., Terriente-Felix, Ana, Sanchez-Martinez, Alvaro, Ziviani, Elena, Whitworth, Alexander J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506686/ https://www.ncbi.nlm.nih.gov/pubmed/31042479 http://dx.doi.org/10.1016/j.celrep.2019.04.033 |
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