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Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics

The cellular responses induced by mitochondrial dysfunction remain elusive. Intrigued by the lack of almost any glomerular phenotype in patients with profound renal ischemia, we comprehensively investigated the primary sources of energy of glomerular podocytes. Combining functional measurements of o...

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Detalles Bibliográficos
Autores principales: Brinkkoetter, Paul T., Bork, Tillmann, Salou, Sarah, Liang, Wei, Mizi, Athanasia, Özel, Cem, Koehler, Sybille, Hagmann, H. Henning, Ising, Christina, Kuczkowski, Alexander, Schnyder, Svenia, Abed, Ahmed, Schermer, Bernhard, Benzing, Thomas, Kretz, Oliver, Puelles, Victor G., Lagies, Simon, Schlimpert, Manuel, Kammerer, Bernd, Handschin, Christoph, Schell, Christoph, Huber, Tobias B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506687/
https://www.ncbi.nlm.nih.gov/pubmed/31042480
http://dx.doi.org/10.1016/j.celrep.2019.04.012