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ALDH2 Repression Promotes Lung Tumor Progression via Accumulated Acetaldehyde and DNA Damage()
The major role of aldehyde dehydrogenase 2 family (ALDH2) is to detoxify acetaldehyde (ACE) to non-toxic acetic acid. Many evidences suggest that ALDH2 dysfunction contributes to a variety of human diseases including cancer. However, the biological function and molecular mechanism of ALDH2 in tumor...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506700/ https://www.ncbi.nlm.nih.gov/pubmed/31071657 http://dx.doi.org/10.1016/j.neo.2019.03.008 |