Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer’s disease by remodeling peri-plaque astrocyte structure

Redistribution of the water channel aquaporin-4 (AQP4) away from astrocyte endfeet and into parenchymal processes is a striking histological feature in mouse models of Alzheimer’s disease (AD) and other neurological conditions with prominent astrogliosis. AQP4 redistribution has been proposed to imp...

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Detalles Bibliográficos
Autores principales: Smith, Alex J., Duan, Tianjiao, Verkman, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506955/
https://www.ncbi.nlm.nih.gov/pubmed/31068220
http://dx.doi.org/10.1186/s40478-019-0728-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506955/
https://www.ncbi.nlm.nih.gov/pubmed/31068220
http://dx.doi.org/10.1186/s40478-019-0728-0

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