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Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer’s disease by remodeling peri-plaque astrocyte structure

Redistribution of the water channel aquaporin-4 (AQP4) away from astrocyte endfeet and into parenchymal processes is a striking histological feature in mouse models of Alzheimer’s disease (AD) and other neurological conditions with prominent astrogliosis. AQP4 redistribution has been proposed to imp...

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Detalles Bibliográficos
Autores principales:	Smith, Alex J., Duan, Tianjiao, Verkman, Alan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506955/ https://www.ncbi.nlm.nih.gov/pubmed/31068220 http://dx.doi.org/10.1186/s40478-019-0728-0

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