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Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice

BACKGROUND: Intracerebral hemorrhage (ICH) is a devastating medical emergency with high mortality and severe neurological deficit. ICH-related poor outcomes are due to a combination of pathological processes that could be complicated by secondary insults. TWIK-related K+ channel 1 (TREK-1) is a two-...

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Detalles Bibliográficos
Autores principales: Fang, Yongkang, Tian, Yeye, Huang, Qibao, Wan, Yue, Xu, Li, Wang, Wei, Pan, Dengji, Zhu, Suiqiang, Xie, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506965/
https://www.ncbi.nlm.nih.gov/pubmed/31072336
http://dx.doi.org/10.1186/s12974-019-1485-5