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Novel Hybrid Gels Made of High and Low Molecular Weight Hyaluronic Acid Induce Proliferation and Reduce Inflammation in an Osteoarthritis In Vitro Model Based on Human Synoviocytes and Chondrocytes

High molecular weight hyaluronan (H-HA) has a pivotal role in the maintenance of normal functions of synovial fluid and structure of the articular joint, but it has been shown that its concentration is reduced in patients affected by degenerative cartilage diseases, such as osteoarthritis (OA). The...

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Detalles Bibliográficos
Autores principales: Stellavato, Antonietta, Vassallo, Valentina, La Gatta, Annalisa, Pirozzi, Anna Virginia Adriana, De Rosa, Mario, Balato, Giovanni, D'Addona, Alessio, Tirino, Virginia, Ruosi, Carlo, Schiraldi, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507116/
https://www.ncbi.nlm.nih.gov/pubmed/31179322
http://dx.doi.org/10.1155/2019/4328219