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Integrated omics-based pathway analyses uncover CYP epoxygenase-associated networks as theranostic targets for metastatic triple negative breast cancer

BACKGROUND: Current prognostic tools and targeted therapeutic approaches have limited value for metastatic triple negative breast cancer (TNBC). Building upon current knowledge, we hypothesized that epoxyeicosatrienoic acids (EETs) and related CYP450 epoxygenases may have differential roles in breas...

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Detalles Bibliográficos
Autores principales: Apaya, Maria Karmella, Shiau, Jeng-Yuan, Liao, Guo-Shiou, Liang, Yu-Jen, Chen, Chia-Wei, Yang, Hsin-Chou, Chu, Chi-Hong, Yu, Jyh-Cherng, Shyur, Lie-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507159/
https://www.ncbi.nlm.nih.gov/pubmed/31072371
http://dx.doi.org/10.1186/s13046-019-1187-y