Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice

Our earlier studies demonstrated that cysteine414- (zinc-binding site of mCRY1-) alanine mutant mCRY1 transgenic mice (Tg mice) exhibit diabetes characterized by the reduction of β-cell proliferation and by β-cell dysfunction, presumably caused by senescence-associated secretory phenotype- (SASP-) l...

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Detalles Bibliográficos
Autores principales: Okano, Satoshi, Yasui, Akira, Kanno, Shin-ichiro, Satoh, Kennichi, Igarashi, Masahiko, Nakajima, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265/
https://www.ncbi.nlm.nih.gov/pubmed/31179341
http://dx.doi.org/10.1155/2019/7234549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265/
https://www.ncbi.nlm.nih.gov/pubmed/31179341
http://dx.doi.org/10.1155/2019/7234549

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