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High expression of PIM2 induces HSC proliferation in myelodysplastic syndromes via the IDH1/HIF1-α signaling pathway

PIM2 proto-oncogene, serine/threonine kinase (PIM2) is a serine/threonine protein kinase that is upregulated in different types of cancer and serves essential roles in the regulation of signal transduction cascades, which promote cell survival and cell proliferation. The present study demonstrated t...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoyun, Tian, Mengyue, Ding, Kai, Liu, Hui, Wang, Yangyang, Fu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507299/
https://www.ncbi.nlm.nih.gov/pubmed/31186757
http://dx.doi.org/10.3892/ol.2019.10256