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High expression of PIM2 induces HSC proliferation in myelodysplastic syndromes via the IDH1/HIF1-α signaling pathway
PIM2 proto-oncogene, serine/threonine kinase (PIM2) is a serine/threonine protein kinase that is upregulated in different types of cancer and serves essential roles in the regulation of signal transduction cascades, which promote cell survival and cell proliferation. The present study demonstrated t...
Autores principales: | Liu, Zhaoyun, Tian, Mengyue, Ding, Kai, Liu, Hui, Wang, Yangyang, Fu, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507299/ https://www.ncbi.nlm.nih.gov/pubmed/31186757 http://dx.doi.org/10.3892/ol.2019.10256 |
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