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The effects of BRCA1 expression on the chemosensitivity of gastric cancer cells to platinum agents

Breast cancer type 1 susceptibility protein (BRCA1) is a tumor suppressor gene that encodes a nuclear phosphoprotein, which is involved in homologous recombination to repair DNA double strand breaks and maintain genome stability. When BRCA1 is mutated or altered, DNA damage may not be effectively re...

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Detalles Bibliográficos
Autores principales: Kim, Geon, Kim, Jisu, Han, Su-Young, Hwang, In Gyu, Kim, Hee Sung, Min, Hyeyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507359/
https://www.ncbi.nlm.nih.gov/pubmed/31186713
http://dx.doi.org/10.3892/ol.2019.10169