Propofol Protects Lung Endothelial Barrier Function by Suppression of High-Mobility Group Box 1 (HMGB1) Release and Mitochondrial Oxidative Damage Catalyzed by HMGB1

BACKGROUND: The processes of mechanical ventilation-induced lung injury (VILI) triggers the release of high-mobility group box 1 (HMGB1), a prominent damage-associated molecular pattern (DAMP) family member, which can cause damage to pulmonary vascular endothelial cells. We aimed to determine whethe...

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Detalles Bibliográficos
Autores principales: Feng, Zhou, Wang, Jian-Wei, Wang, Yan, Dong, Wen-Wen, Xu, Zi-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507496/
https://www.ncbi.nlm.nih.gov/pubmed/31040263
http://dx.doi.org/10.12659/MSM.915417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507496/
https://www.ncbi.nlm.nih.gov/pubmed/31040263
http://dx.doi.org/10.12659/MSM.915417

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