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Proteolytic cleavages of MET: the divide-and-conquer strategy of a receptor tyrosine kinase

Membrane-anchored full-length MET stimulated by its ligand HGF/SF induces various biological responses, including survival, growth, and invasion. This panel of responses, referred to invasive growth, is required for embryogenesis and tissue regeneration in adults. On the contrary, MET deregulation i...

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Detalles Bibliográficos
Autores principales: Fernandes, Marie, Duplaquet, Leslie, Tulasne, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507848/
https://www.ncbi.nlm.nih.gov/pubmed/30670153
http://dx.doi.org/10.5483/BMBRep.2019.52.4.024