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Interleukin-2/antibody complex expanding Foxp3+ regulatory T cells exacerbates Th2-mediated allergic airway inflammation

Foxp3(+) regulatory CD4(+) T (Treg) cells play an essential role in preventing overt immune responses against self and innocuous foreign antigens. Selective expansion of endogenous Treg cells in response to the administration of interleukin (IL)-2/antibody complex, such as the IL-2/JES6-1 complex (I...

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Detalles Bibliográficos
Autores principales: Hong, Sung-Wook, Eunju, O, Lee, Jun Young, Yi, Jaeu, Cho, Kyungjin, Kim, Juhee, Kim, Daeun, Surh, Charles D., Kim, Kwang Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507850/
https://www.ncbi.nlm.nih.gov/pubmed/30885291
http://dx.doi.org/10.5483/BMBRep.2019.52.4.271