An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis

Anti-TNF agents have been in the first line of treatment of various inflammatory diseases such as Rheumatoid Arthritis and Crohn’s Disease, with a number of different biologics being currently in use. A detailed analysis of their effect at transcriptome level has nevertheless been lacking. We herein...

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Detalles Bibliográficos
Autores principales: Karagianni, Niki, Kranidioti, Ksanthi, Fikas, Nikolaos, Tsochatzidou, Maria, Chouvardas, Panagiotis, Denis, Maria C., Kollias, George, Nikolaou, Christoforos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508611/
https://www.ncbi.nlm.nih.gov/pubmed/31071076
http://dx.doi.org/10.1371/journal.pcbi.1006933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508611/
https://www.ncbi.nlm.nih.gov/pubmed/31071076
http://dx.doi.org/10.1371/journal.pcbi.1006933

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