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Satellite DNA-containing gigantic introns in a unique gene expression program during Drosophila spermatogenesis

Intron gigantism, where genes contain megabase-sized introns, is observed across species, yet little is known about its purpose or regulation. Here we identify a unique gene expression program utilized for the proper expression of genes with intron gigantism. We find that two Drosophila genes with i...

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Detalles Bibliográficos
Autores principales: Fingerhut, Jaclyn M., Moran, Jessica V., Yamashita, Yukiko M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508621/
https://www.ncbi.nlm.nih.gov/pubmed/31071079
http://dx.doi.org/10.1371/journal.pgen.1008028