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Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons
Loss of the nuclear RNA binding protein TAR DNA binding protein-43 (TDP-43) into cytoplasmic aggregates is the strongest correlate to neurodegeneration in amyotrophic lateral sclerosis and frontotemporal degeneration. The molecular changes associated with the loss of nuclear TDP-43 in human tissues...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508629/ https://www.ncbi.nlm.nih.gov/pubmed/31042469 http://dx.doi.org/10.1016/j.celrep.2019.04.003 |