Cargando…

Lysozyme as the anti-proliferative agent to block the interaction between S100A6 and the RAGE V domain

In this report, using NMR and molecular modeling, we have studied the structure of lysozyme-S100A6 complex and the influence of tranilast [N-(3, 4-dimethoxycinnamoyl) anthranilic acid], an antiallergic drug which binds to lysozyme, on lysozyme-S100A6 and S100A6-RAGE complex formation and, finally, o...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Md. Imran, Dowarha, Deepu, Katte, Revansiddha, Chou, Ruey-Hwang, Filipek, Anna, Yu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508705/
https://www.ncbi.nlm.nih.gov/pubmed/31071146
http://dx.doi.org/10.1371/journal.pone.0216427