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The nonlinear dynamics and fluctuations of mRNA levels in cell cycle coupled transcription

Gene transcription is a noisy process, and cell division cycle is an important source of gene transcription noise. In this work, we develop a mathematical approach by coupling transcription kinetics with cell division cycles to delineate how they are combined to regulate transcription output and noi...

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Detalles Bibliográficos
Autores principales: Sun, Qiwen, Jiao, Feng, Lin, Genghong, Yu, Jianshe, Tang, Moxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508750/
https://www.ncbi.nlm.nih.gov/pubmed/31034470
http://dx.doi.org/10.1371/journal.pcbi.1007017