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The nonlinear dynamics and fluctuations of mRNA levels in cell cycle coupled transcription
Gene transcription is a noisy process, and cell division cycle is an important source of gene transcription noise. In this work, we develop a mathematical approach by coupling transcription kinetics with cell division cycles to delineate how they are combined to regulate transcription output and noi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508750/ https://www.ncbi.nlm.nih.gov/pubmed/31034470 http://dx.doi.org/10.1371/journal.pcbi.1007017 |