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MicroRNA MIMIC binding sites: Minor flanking nucleotide alterations can strongly impact MIMIC silencing efficacy in Arabidopsis

In plants, microRNA (miRNA) target MIMICs (MIMs) have been widely used to inhibit miRNA function. They are based on the Arabidopsis INSENSITIVE TO PHOSPATE STARVATION 1 (IPS1) gene that corresponds to a non‐coding RNA containing a miR399 binding site that can be modified to sequester and inhibit any...

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Detalles Bibliográficos
Autores principales: Wong, Gigi, Alonso‐Peral, Maria, Li, Bingjun, Li, Junyan, Millar, Anthony A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508833/
https://www.ncbi.nlm.nih.gov/pubmed/31245688
http://dx.doi.org/10.1002/pld3.88