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Circulating transforming growth factor-β1 facilitates remyelination in the adult central nervous system

Oligodendrocyte maturation is necessary for functional regeneration in the CNS; however, the mechanisms by which the systemic environment regulates oligodendrocyte maturation is unclear. We found that Transforming growth factor (TGF)-β1, which is present in higher levels in the systemic environment,...

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Detalles Bibliográficos
Autores principales: Hamaguchi, Machika, Muramatsu, Rieko, Fujimura, Harutoshi, Mochizuki, Hideki, Kataoka, Hirotoshi, Yamashita, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508935/
https://www.ncbi.nlm.nih.gov/pubmed/31071011
http://dx.doi.org/10.7554/eLife.41869