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Thyroid hormones induce doxorubicin chemosensitivity through enzymes involved in chemotherapy metabolism in lymphoma T cells

Thyroid hormones (THs) – 3,3′,5-triiodo-L-thyronine (T3) and L-thyroxine (T4) – are important regulators of the metabolism and physiology of most normal tissues. Cytochrome P450 family 3A members are drug metabolizing enzymes involved in the activation and detoxification of several drugs. CYP3A4 is...

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Detalles Bibliográficos
Autores principales: Díaz Flaqué, María Celeste, Cayrol, Maria Florencia, Sterle, Helena Andrea, del Rosario Aschero, María, Díaz Albuja, Johanna Abigail, Isse, Blanca, Farías, Ricardo Norberto, Cerchietti, Leandro, Rosemblit, Cinthia, Cremaschi, Graciela Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508960/
https://www.ncbi.nlm.nih.gov/pubmed/31105885
http://dx.doi.org/10.18632/oncotarget.26890