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Secretomes from metastatic breast cancer cells, enriched for a prognostically unfavorable LCN2 axis, induce anti-inflammatory MSC actions and a tumor-supportive premetastatic lung

Cancer metastasis is responsible for the clear majority of cancer-related deaths. Survival and expansion of cancer cells at secondary sites requires that these premetastatic microenvironments be primed by primary tumor cells and their secreted factors. Efforts to date have been limited by immune-def...

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Detalles Bibliográficos
Autores principales: Meade, Kayla J., Sanchez, Francesca, Aguayo, Analine, Nadales, Nathalie, Hamalian, Sarkis G., Uhlendorf, Toni L., Banner, Lisa R., Kelber, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508963/
https://www.ncbi.nlm.nih.gov/pubmed/31105883
http://dx.doi.org/10.18632/oncotarget.26903