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Mutant huntingtin disturbs circadian clock gene expression and sleep patterns in Drosophila
Deficiency of the sleep-wake cycle can accelerate the progression of Huntington’s disease (HD) and exacerbate symptoms making it a target of investigation to better understand the molecular pathology of the disorder. In this study we analyzed sleep defects in a Drosophila model of HD and investigate...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509128/ https://www.ncbi.nlm.nih.gov/pubmed/31073199 http://dx.doi.org/10.1038/s41598-019-43612-w |