Defective Expression of Mitochondrial, Vacuolar H(+)-ATPase and Histone Genes in a C. elegans Model of SMA

Spinal muscular atrophy (SMA) is a severe motor neuron degenerative disease caused by loss-of-function mutations in the survival motor neuron gene SMN1. It is widely posited that defective gene expression underlies SMA. However, the identities of these affected genes remain to be elucidated. By anal...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Xiaoyang, Xu, Jing, Chen, Hao, Xue, Dingwu, Pan, Wenju, Zhou, Chuanman, Ma, Yongchao C., Ma, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509145/
https://www.ncbi.nlm.nih.gov/pubmed/31130987
http://dx.doi.org/10.3389/fgene.2019.00410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509145/
https://www.ncbi.nlm.nih.gov/pubmed/31130987
http://dx.doi.org/10.3389/fgene.2019.00410

Ejemplares similares