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Reduced Angiopoietin-Like 4 Expression in Multiple Sclerosis Lesions Facilitates Lipid Uptake by Phagocytes via Modulation of Lipoprotein-Lipase Activity

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) characterized by the presence of focal demyelinated plaques. Sufficient clearance of myelin and cellular debris is one of the requirements for proper tissue repair and remyelination. The mechanisms underly...

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Detalles Bibliográficos
Autores principales: Kamermans, Alwin, Rijnsburger, Merel, Chakraborty, Ananya, van der Pol, Susanne, de Vries, Helga E., van Horssen, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509157/
https://www.ncbi.nlm.nih.gov/pubmed/31130950
http://dx.doi.org/10.3389/fimmu.2019.00950