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Assessing mitochondrial heteroplasmy using next generation sequencing: A note of caution
The mitochondrial genome has recently become the focus of several high-impact next-generation sequencing studies investigating the effect of mutations in disease and assessing the efficacy of mitochondrial replacement therapies. However, these studies have failed to take into consideration the captu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509278/ https://www.ncbi.nlm.nih.gov/pubmed/30098421 http://dx.doi.org/10.1016/j.mito.2018.08.003 |