Cargando…
Assessing mitochondrial heteroplasmy using next generation sequencing: A note of caution
The mitochondrial genome has recently become the focus of several high-impact next-generation sequencing studies investigating the effect of mutations in disease and assessing the efficacy of mitochondrial replacement therapies. However, these studies have failed to take into consideration the captu...
Autores principales: | Santibanez-Koref, Mauro, Griffin, Helen, Turnbull, Douglass M., Chinnery, Patrick F., Herbert, Mary, Hudson, Gavin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509278/ https://www.ncbi.nlm.nih.gov/pubmed/30098421 http://dx.doi.org/10.1016/j.mito.2018.08.003 |
Ejemplares similares
-
Universal heteroplasmy of human mitochondrial DNA
por: Payne, Brendan A.I., et al.
Publicado: (2013) -
Feasibility and impact of haplogroup matching for mitochondrial replacement treatment
por: Takeda, Yuko, et al.
Publicado: (2023) -
Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans
por: Pyle, Angela, et al.
Publicado: (2015) -
Mitochondrial heteroplasmy profiling in single human oocytes by next-generation sequencing
por: Ancora, Massimo, et al.
Publicado: (2017) -
Circulating cell-free mitochondrial DNA levels in Parkinson’s disease are influenced by treatment
por: Lowes, Hannah, et al.
Publicado: (2020)