Cargando…

Assessing mitochondrial heteroplasmy using next generation sequencing: A note of caution

The mitochondrial genome has recently become the focus of several high-impact next-generation sequencing studies investigating the effect of mutations in disease and assessing the efficacy of mitochondrial replacement therapies. However, these studies have failed to take into consideration the captu...

Descripción completa

Detalles Bibliográficos
Autores principales: Santibanez-Koref, Mauro, Griffin, Helen, Turnbull, Douglass M., Chinnery, Patrick F., Herbert, Mary, Hudson, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509278/
https://www.ncbi.nlm.nih.gov/pubmed/30098421
http://dx.doi.org/10.1016/j.mito.2018.08.003

Ejemplares similares