Inheritance of a Phenotypically Neutral Epimutation Evokes Gene Silencing in Later Generations

Small RNAs trigger the formation of epialleles that are silenced across generations. Consequently, RNA-directed epimutagenesis is associated with persistent gene repression. Here, we demonstrate that small interfering RNA-induced epimutations in fission yeast are still inherited even when the silenc...

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Detalles Bibliográficos
Autores principales: Duempelmann, Lea, Mohn, Fabio, Shimada, Yukiko, Oberti, Daniele, Andriollo, Aude, Lochs, Silke, Bühler, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509282/
https://www.ncbi.nlm.nih.gov/pubmed/30898439
http://dx.doi.org/10.1016/j.molcel.2019.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509282/
https://www.ncbi.nlm.nih.gov/pubmed/30898439
http://dx.doi.org/10.1016/j.molcel.2019.02.009

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