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A microbiota-generated bile salt induces biofilm formation in Clostridium difficile

Clostridium difficile is a major cause of nosocomial infections. Bacterial persistence in the gut is responsible for infection relapse; sporulation and other unidentified mechanisms contribute to this process. Intestinal bile salts cholate and deoxycholate stimulate spore germination, while deoxycho...

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Detalles Bibliográficos
Autores principales: Dubois, Thomas, Tremblay, Yannick D. N., Hamiot, Audrey, Martin-Verstraete, Isabelle, Deschamps, Julien, Monot, Marc, Briandet, Romain, Dupuy, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509328/
https://www.ncbi.nlm.nih.gov/pubmed/31098293
http://dx.doi.org/10.1038/s41522-019-0087-4