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A microbiota-generated bile salt induces biofilm formation in Clostridium difficile
Clostridium difficile is a major cause of nosocomial infections. Bacterial persistence in the gut is responsible for infection relapse; sporulation and other unidentified mechanisms contribute to this process. Intestinal bile salts cholate and deoxycholate stimulate spore germination, while deoxycho...
Autores principales: | Dubois, Thomas, Tremblay, Yannick D. N., Hamiot, Audrey, Martin-Verstraete, Isabelle, Deschamps, Julien, Monot, Marc, Briandet, Romain, Dupuy, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509328/ https://www.ncbi.nlm.nih.gov/pubmed/31098293 http://dx.doi.org/10.1038/s41522-019-0087-4 |
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