SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer

Approximately 30% of ERα breast cancer patients relapse with metastatic disease following adjuvant endocrine therapies. The connection between acquisition of drug resistance and invasive potential is poorly understood. In this study, we demonstrate that the type II keratin topological associating do...

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Detalles Bibliográficos
Autores principales: Perone, Ylenia, Farrugia, Aaron J., Rodríguez-Meira, Alba, Győrffy, Balázs, Ion, Charlotte, Uggetti, Andrea, Chronopoulos, Antonios, Marrazzo, Pasquale, Faronato, Monica, Shousha, Sami, Davies, Claire, Steel, Jennifer H., Patel, Naina, del Rio Hernandez, Armando, Coombes, Charles, Pruneri, Giancarlo, Lim, Adrian, Calvo, Fernando, Magnani, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509342/
https://www.ncbi.nlm.nih.gov/pubmed/31073170
http://dx.doi.org/10.1038/s41467-019-09676-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509342/
https://www.ncbi.nlm.nih.gov/pubmed/31073170
http://dx.doi.org/10.1038/s41467-019-09676-y

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