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Novel CMKLR1 Inhibitors for Application in Demyelinating Disease

Small molecules that disrupt leukocyte trafficking have proven effective in treating patients with multiple sclerosis (MS). We previously reported that chemerin receptor chemokine-like receptor 1 (CMKLR1) is required for maximal clinical and histological experimental autoimmune encephalomyelitis (EA...

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Detalles Bibliográficos
Autores principales: Kumar, Vineet, LaJevic, Melissa, Pandrala, Mallesh, Jacobo, Sam A., Malhotra, Sanjay V., Zabel, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509344/
https://www.ncbi.nlm.nih.gov/pubmed/31073181
http://dx.doi.org/10.1038/s41598-019-43428-8