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Histone H2A insufficiency causes chromosomal segregation defects due to anaphase chromosome bridge formation at rDNA repeats in fission yeast

The nucleosome, composed of DNA and a histone core, is the basic structural unit of chromatin. The fission yeast Schizosaccharomyces pombe has two genes of histone H2A, hta1(+) and hta2(+); these genes encode two protein species of histone H2A (H2Aα and H2Aβ, respectively), which differ in three ami...

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Detalles Bibliográficos
Autores principales: Yamamoto, Takaharu G., Ding, Da-Qiao, Nagahama, Yuki, Chikashige, Yuji, Haraguchi, Tokuko, Hiraoka, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509349/
https://www.ncbi.nlm.nih.gov/pubmed/31073221
http://dx.doi.org/10.1038/s41598-019-43633-5