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Histone H2A insufficiency causes chromosomal segregation defects due to anaphase chromosome bridge formation at rDNA repeats in fission yeast
The nucleosome, composed of DNA and a histone core, is the basic structural unit of chromatin. The fission yeast Schizosaccharomyces pombe has two genes of histone H2A, hta1(+) and hta2(+); these genes encode two protein species of histone H2A (H2Aα and H2Aβ, respectively), which differ in three ami...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509349/ https://www.ncbi.nlm.nih.gov/pubmed/31073221 http://dx.doi.org/10.1038/s41598-019-43633-5 |