Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity

The evolutionarily related deubiquitinating enzymes (DUBs) USP25 and USP28 comprise an identical overall domain architecture but are functionally non-redundant: USP28 stabilizes c-MYC and other nuclear proteins, and USP25 regulates inflammatory TRAF signaling. We here compare molecular features of U...

Descripción completa

Detalles Bibliográficos
Autores principales: Gersch, Malte, Wagstaff, Jane L., Toms, Angela V., Graves, Bradford, Freund, Stefan M.V., Komander, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509359/
https://www.ncbi.nlm.nih.gov/pubmed/30926242
http://dx.doi.org/10.1016/j.molcel.2019.02.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509359/
https://www.ncbi.nlm.nih.gov/pubmed/30926242
http://dx.doi.org/10.1016/j.molcel.2019.02.030

Ejemplares similares