Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

Expansion of transposable elements (TEs) coincides with evolutionary shifts in gene expression. TEs frequently harbor binding sites for transcriptional regulators, thus enabling coordinated genome-wide activation of species- and context-specific gene expression programs, but such regulation must be...

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Detalles Bibliográficos
Autores principales: Pontis, Julien, Planet, Evarist, Offner, Sandra, Turelli, Priscilla, Duc, Julien, Coudray, Alexandre, Theunissen, Thorold W., Jaenisch, Rudolf, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509360/
https://www.ncbi.nlm.nih.gov/pubmed/31006620
http://dx.doi.org/10.1016/j.stem.2019.03.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509360/
https://www.ncbi.nlm.nih.gov/pubmed/31006620
http://dx.doi.org/10.1016/j.stem.2019.03.012

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