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Inhibition of Period Gene Expression Causes Repression of Cell Cycle Progression and Cell Growth in the Bombyx mori Cells

Circadian clock system disorders can lead to uncontrolled cell proliferation, but the molecular mechanism remains unknown. We used a Bombyx mori animal model of single Period gene (BmPer) expression to investigate this mechanism. A slow growing developmental cell model (Per-KD) was isolated from a B...

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Detalles Bibliográficos
Autores principales: Qiu, Jian-Feng, Li, Xue, Cui, Wen-Zhao, Liu, Xiao-Fei, Tao, Hui, Yang, Kun, Dai, Tai-Ming, Sima, Yang-Hu, Xu, Shi-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509393/
https://www.ncbi.nlm.nih.gov/pubmed/31130878
http://dx.doi.org/10.3389/fphys.2019.00537